While longevity is often associated with lifespan, it’s more accurately about extending "healthspan"—the portion of life spent in good health. One promising breakthrough in longevity science is NMN. NMN is a supplement that serves as a precursor to NAD+, a vital molecule responsible for regulating cellular functions. NAD+ plays a critical role in overall well-being by maintaining cellular health, supporting energy production and repairing DNA.
NMN is quickly gaining recognition as one of the most researched and effective supplements for promoting longevity and anti-aging, making it a top choice for those looking to extend their healthspan and live long, vibrant lives.
What is NAD+?
NAD+ is a foundational molecule that orchestrates many intracellular processes. It most notably repairs and protects DNA which is an essential component to longevity. In addition, it regulates gene expression, supports the creation of new mitochondria and is a key driver of energy production.
Research suggests that NAD+ production declines by more than 50% as we age and low levels of NAD+ are believed to drive processes that can contribute to disease.
When the production of NAD+ decreases we see:
1. An Accelerated Cellular Aging Process: this contributes to abnormal cell function, which in turn negatively impacts the body as a whole
2. Higher Rates of DNA Damage: overtime, this leads to mutations and can catalyze the processes of chronic illness such as cancer
3. An Increase in the Hallmarks of Aging: low levels of NAD are seen alongside an increase in biological age that is measured by telomere length and altered mitochondrial function. This can show up as premature wrinkles and outward expressions of aging or as a functional breakdown of tissues
An NMN supplement can slow down cellular and biological aging while preventing DNA mutations by restoring NAD+ levels.
Increasing NMN has been shown to tangibly improve quality of life - meaning you’ll notice the effects of NMN supplementation in your everyday life.
5 Key NMN Benefits
1) Weight Loss
NMN is one of the best supplements for weight loss, as weight loss is often observed in those taking it. This is largely due to its ability to regulate how the body processes sugar. Poor glucose management is a hallmark of aging and can make weight loss difficult. NMN can help to regulate this issue- facilitating healthy and easy weight loss.
Another reason weight loss is seen with NMN is because it activates a class of proteins called sirtuins, which play a key role in controlling cellular metabolism. This promotes natural, healthy weight loss. One particular sirtuin, often referred to as the "skinny gene," is especially influenced by the increased NAD+ from NMN, enhancing the body's fat-burning capacity.
2) NMN For Energy
NMN has been shown to reduce fatigue and boost energy without the jittery effects of stimulants.
It’s believed to work by increasing both the quality and quantity of mitochondria—those tiny powerhouses in your cells that produce ATP, the molecule of energy.
Most people experience an immediate boost in energy after taking NMN, and with regular use, this can gradually become your new normal.
3) Better Brain Health
NAD+ is essential for maintaining a healthy brain. It acts as an overall neuro-protector by extending the lifespan of brain cells and shielding them from damage.
Research shows that supplementing with NMN can boost brain NAD levels. This has neuroprotective effects that may help prevent diseases like Alzheimer’s and dementia. In the short term, NMN can also clear brain fog, enhance alertness, and improve memory recall.
For both short- and long-term cognitive health, NMN is a smart choice.
4) Greater stamina and strength
When taken over an extended period, NMN has been shown to improve key fitness markers, including stamina, muscle strength, and grip strength - all predictors of longevity.
Increased stamina: NMN supplementation has been linked to enhanced endurance by delaying fatigue in activities like walking and running. When NAD levels are increased, studies report faster gait speeds and quicker run times.
Increased strength: A clinical trial demonstrated that 250mg of NMN daily can boost muscle strength, particularly in older adults.
Grip Strength: This is a reliable indicator of overall muscle health. A weaker grip is linked to a higher risk of metabolic and cardiovascular diseases- and NMN has been shown to help improve it.
5) Radiant Skin
Increases in NAD have been correlated with slower skin aging. Recent studies and clinical trials have demonstrated NMN can:
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Safeguard skin from damage brought on by UV light
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Decrease AGES, which are proteins that get bound up in the skin matrix and contribute to a loss of skin elasticity
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Increase a particular sirtuin (SIRT3) that is well known for its fundamental role in skin health
Additionally, supplementing with NMN has been shown to preserve and increase collagen while reducing inflammation in the skin leading to a youthful, more radiant complexion even as the decades pass.
Honorary Mentions
NMN is quickly becoming one of the most thoroughly researched nutritional supplements, and its full potential is just beginning to be uncovered. While ongoing research continues to explore the precise mechanisms and far-reaching effects on human health, early findings are already showing incredible promise across a range of areas:
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Insulin Sensitivity: NMN helps regulate glucose tolerance and blood sugar levels, making it a strong contender for diabetes management
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Eye Health: Studies suggest NMN reduces retinal damage and ocular inflammation, offering vision protection throughout the lifespan
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Immunity: By boosting white blood cell production, NMN strengthens the body’s ability to fight off infections
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Sleep: Clinical trials show that taking NMN in the afternoon improves sleep quality, helping you wake up feeling more refreshed
With each new discovery, NMN is proving to be a game-changer in supporting health and vitality, making it an exciting option for those looking to enhance their well-being from the inside out.
NMN stands out as a powerful tool for supporting longevity by enhancing NAD+ levels—a critical molecule that declines with age and impacts everything from energy production to DNA repair. The science behind NMN suggests it plays a pivotal role in slowing down cellular aging, improving metabolic health, and enhancing overall vitality. Whether it’s boosting brain function, improving physical strength, or even rejuvenating the skin, NMN offers tangible benefits that go beyond just extending lifespan, it supports a healthier, more vibrant healthspan. With its wide array of positive effects, NMN is truly an exceptional choice for those looking to maintain youthfulness and vitality as they age.
Try it for yourself- AORS NMN + Wheat Germ is our top pick!
Author: Lisa Kowalyk, CNP, B.Kin