Thanks to mental health advocates, research funds and resources are being allocated to pathologies such as depression. Traditional approaches to manage depression often fall short. For this reason there is a large body of research on natural ways to combat depressive symptom. One area of interest is that of the role of carnitine is both onset and symptomatic relief. This article dives into the current research that shows low ALCAR levels are found in a large percent of people who experience depression, and the positive effects of supplemental ALCAR on depression symptoms.